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What the FDA labels say about taking them together

Cyclosporine and valganciclovir

Valganciclovir's FDA label of December 8, 2025 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name valganciclovir. The valganciclovir label: “Monitor renal function when VALCYTE is coadministered with cyclosporine or amphotericin B because of potential increase in serum creatinine.”

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the valganciclovir FDA label on DailyMed (effective December 8, 2025, H2-Pharma, LLC).

What does the cyclosporine label say about valganciclovir?

Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name valganciclovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the valganciclovir label say about cyclosporine?

Valganciclovir label, drug interactions

Name of the Concomitant Drug: Cyclosporine or amphotericin B; Change in the Concentration of Ganciclovir or Concomitant Drug: Unknown; Clinical Comment: Monitor renal function when VALCYTE is coadministered with cyclosporine or amphotericin B because of potential increase in serum creatinine [see ].

Source: FDA drug label (Valcyte), NDA021304 (Cheplapharm), as published by H2-Pharma, LLC, effective December 8, 2025 (SPL set 4c517a39-2ded-4c5a-8d56-276853414b31), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
19Valganciclovir generic labelers
CyclosporineValganciclovir
Labeled forOrgan transplant rejection, Rheumatoid arthritisn/a
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsion$1.91 per tablet 450 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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