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What the FDA labels say about taking them together

Trastuzumab and trastuzumab emtansine

Trastuzumab emtansine's FDA label of April 1, 2026 names trastuzumab in its warnings and precautions section; the trastuzumab labels PlainMeds reads (4) do not name trastuzumab emtansine. The trastuzumab emtansine label: “Treatment with KADCYLA has not been studied in patients who had trastuzumab permanently discontinued due to infusion-related reactions (IRRs) and/or hypersensitivity; …”

Check it at the source: the trastuzumab FDA label on DailyMed (effective May 29, 2026, Genentech, Inc.); the trastuzumab emtansine FDA label on DailyMed (effective April 1, 2026).

What does the trastuzumab label say about trastuzumab emtansine?

Trastuzumab's label (effective May 29, 2026) and its 3 other brand-application labels do not name trastuzumab emtansine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Herceptin), Genentech, Inc., effective May 29, 2026 (SPL set 492dbdb2-077e-4064-bff3-372d6af0a7a2), via openFDA; the full label on DailyMed

What does the trastuzumab emtansine label say about trastuzumab?

Trastuzumab emtansine label, warnings and precautions

Treatment with KADCYLA has not been studied in patients who had trastuzumab permanently discontinued due to infusion-related reactions (IRRs) and/or hypersensitivity; treatment with KADCYLA is not recommended for these patients.

Source: FDA drug label (KADCYLA), Genentech, Inc., effective April 1, 2026 (SPL set 23f3c1f4-0fc8-4804-a9e3-04cf25dd302e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Trastuzumab generic labelers
0Trastuzumab emtansine generic labelers
TrastuzumabTrastuzumab emtansine
Labeled forBreast cancerBreast cancer
Boxed warningYesYes
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?