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What the FDA labels say about taking them together

Dopamine and tranylcypromine

Dopamine's FDA label of May 12, 2026 names tranylcypromine in its drug interactions section; the tranylcypromine label PlainMeds reads does not name dopamine.

Check it at the source: the dopamine FDA label on DailyMed (effective May 12, 2026, Hospira, Inc.); the tranylcypromine FDA label on DailyMed (effective July 2, 2025, Advanz Pharma (US) Corp.).

What does the dopamine label say about tranylcypromine?

Dopamine label, drug interactions

MAO Inhibitors Clinical Impact: Because dopamine is metabolized by monoamine oxidase (MAO), inhibition of this enzyme prolongs and potentiates the effect of dopamine which may result in severe hypertension and cardiac arrhythmia. … prior to the administration of Dopamine HCl in Dextrose Injection. Examples: isocarboxazid, phenelzine, tranylcypromine, rasagiline, selegiline, linezolid.

Source: FDA drug label (Dopamine Hydrochloride in Dextrose), Hospira, Inc., effective May 12, 2026 (SPL set 08f23f6e-150d-45ea-098e-f2edf64c21a1), via openFDA; the full label on DailyMed

What does the tranylcypromine label say about dopamine?

Tranylcypromine's label (effective July 2, 2025) does not name dopamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (PARNATE), Advanz Pharma (US) Corp., effective July 2, 2025 (SPL set b72d8187-dfcc-4ea0-b5e9-c0be95b69a27), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Dopamine generic labelers
4Tranylcypromine generic labelers
DopamineTranylcypromine
Labeled forn/aDepression
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.591 per tablet 10 mg tablet
Shortage nowIn shortageA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?