Skip to main content

What the FDA labels say about taking them together

Clarithromycin and ticagrelor

Ticagrelor's FDA label of May 7, 2026 names clarithromycin in its drug interactions section; the clarithromycin label PlainMeds reads does not name ticagrelor. The ticagrelor label: “Avoid use of strong inhibitors of CYP3A.”

Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the ticagrelor FDA label on DailyMed (effective May 7, 2026, AstraZeneca Pharmaceuticals LP).

What does the clarithromycin label say about ticagrelor?

Clarithromycin's label (effective April 9, 2026) does not name ticagrelor in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed

What does the ticagrelor label say about clarithromycin?

Ticagrelor label, drug interactions

Avoid use of strong inhibitors of CYP3A (e.g., ketoconazole, itraconazole, voriconazole, clarithromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir, atazanavir and telithromycin) [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (BRILINTA), AstraZeneca Pharmaceuticals LP, effective May 7, 2026 (SPL set f7b3f443-e83d-4bf2-0e96-023448fed9a8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

26Clarithromycin generic labelers
28Ticagrelor generic labelers
ClarithromycinTicagrelor
Labeled forBacterial infections, Acid reflux and ulcersHeart attack and coronary artery disease, Stroke prevention
Boxed warningNoYes
Pharmacy cost (NADAC)$0.466 per tablet 500 mg tablet$0.253 per tablet 90 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?