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What the FDA labels say about taking them together

Hydrocortisone and theophylline

Theophylline's FDA label of March 10, 2026 names hydrocortisone in its drug interactions section; the hydrocortisone labels PlainMeds reads (4) do not name theophylline.

Check it at the source: the hydrocortisone FDA label on DailyMed (effective August 19, 2026); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).

What does the hydrocortisone label say about theophylline?

Hydrocortisone's label (effective August 19, 2026) and its 3 other brand-application labels do not name theophylline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (hydrocortisone 1), Kroger Company, effective August 19, 2026 (SPL set f05edff2-2dc5-427c-b52c-518e0aaef4e0), via openFDA; the full label on DailyMed

What does the theophylline label say about hydrocortisone?

Theophylline label, drug interactions

hydrocortisone; theophylline absorption)

Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

49Hydrocortisone generic labelers
26Theophylline generic labelers
HydrocortisoneTheophylline
Labeled forOsteoarthritis, Asthma, Allergies, Herpes and shingles, Leukemia, lymphoma and myeloma, Crohn's disease and ulcerative colitis, Eczema (atopic dermatitis)Asthma
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0613 per gram 1% cream$0.330 per tablet 300 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?