What the FDA labels say about taking them together
Thalidomide and vincristine
Thalidomide's FDA label of March 24, 2023 names vincristine in its drug interactions section; the vincristine label PlainMeds reads does not name thalidomide.
Check it at the source: the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation); the vincristine FDA label on DailyMed (effective February 17, 2026, Hospira, Inc.).
What does the thalidomide label say about vincristine?
Thalidomide label, drug interactionsDrugs which Cause Peripheral Neuropathy The use of drugs which cause peripheral neuropathy (e.g., bortezomib, amiodarone, cisplatin, docetaxel, paclitaxel, vincristine, disulfiram, phenytoin, metronidazole, alcohol) can cause an additive effect and should be used with caution.
Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed
What does the vincristine label say about thalidomide?
Vincristine's label (effective February 17, 2026) does not name thalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VinCRIStine Sulfate), Hospira, Inc., effective February 17, 2026 (SPL set b22e4c8e-dbe1-4d4b-a026-e1812974071c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Thalidomide | Vincristine | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once