What the FDA labels say about taking them together
Teriflunomide and theophylline
Teriflunomide's FDA label of February 20, 2026 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name teriflunomide. The teriflunomide label: “In patients taking AUBAGIO, exposure of drugs metabolized by CYP1A2 may be reduced.”
Check it at the source: the teriflunomide FDA label on DailyMed (effective February 20, 2026, Genzyme Corporation); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the teriflunomide label say about theophylline?
Teriflunomide label, drug interactionsIn patients taking AUBAGIO, exposure of drugs metabolized by CYP1A2 (e.g., alosetron, duloxetine, theophylline, tizanidine) may be reduced.
Source: FDA drug label (Aubagio), NDA202992 (Sanofi Aventis Us), as published by Genzyme Corporation, effective February 20, 2026 (SPL set 4650d12c-b9c8-4525-b07f-a2d773eca155), via openFDA; the full label on DailyMed
What does the theophylline label say about teriflunomide?
Theophylline's label (effective March 10, 2026) does not name teriflunomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Teriflunomide | Theophylline | |
|---|---|---|
| Labeled for | Multiple sclerosis | Asthma |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.233 per tablet 14 mg tablet | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once