Methylprednisolone · more major-labeled pairs than Tacrolimus Topical

SPL labels Tacrolimus Topical + Methylprednisolone as minor; Tacrolimus Topical 6 / Methylprednisolone 22 in that band.

Mechanism on file: Methylprednisolone makes your liver work faster to break down tacrolimus, which can lower the amount of medicine in your blood.

FDA SPL severity: Minor

Tacrolimus Topical

Full Tacrolimus Topical label record

Calcineurin Inhibitor (Topical)

Methylprednisolone

Full Methylprednisolone label record

Corticosteroid

Tacrolimus Topical + Methylprednisolone · SPL mechanism field

Methylprednisolone makes your liver work faster to break down tacrolimus, which can lower the amount of medicine in your blood.

Minor band excerpt · Tacrolimus Topical with Methylprednisolone

Mild or Moderate CYP3A Inducers Methylprednisolone, prednisone May decrease tacrolimus whole blood trough concentrations.

Tacrolimus Topical · 6 minor + 25 total pairs

View all Tacrolimus Topical interactions →

Methylprednisolone · 1 major-labeled pairs (vs Tacrolimus Topical's 0)

View all Methylprednisolone interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.