Cyclosporine · more major-labeled pairs than Tacrolimus Topical
SPL labels Tacrolimus Topical + Cyclosporine as minor; Tacrolimus Topical 6 / Cyclosporine 60 in that band.
Mechanism on file: These drugs change how medicines move through your digestive system and liver in different ways, which can affect your blood levels.
FDA SPL severity: Minor
Tacrolimus Topical + Cyclosporine · SPL mechanism field
These drugs change how medicines move through your digestive system and liver in different ways, which can affect your blood levels.
Minor band excerpt · Tacrolimus Topical with Cyclosporine
( 7.1 , 7.2 , 7.3 ) 7.1 Mycophenolic Acid When tacrolimus extended-release capsules is prescribed with a given dose of a mycophenolic acid (MPA) product, exposure to MPA is higher with tacrolimus extended-release capsules co-administration than with cyclosporine co-administration with MPA, because cyclosporine interrupts the enterohepatic recirculation of MPA while tacrolimus does not.
Tacrolimus Topical · 6 minor + 25 total pairs
- Cannabidiol minor
- Caspofungin minor
- Methylprednisolone minor
- Midazolam minor
Cyclosporine · 5 major-labeled pairs (vs Tacrolimus Topical's 0)
- Adalimumab minor
- Amiodarone minor
- Amlodipine minor
- Anidulafungin minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.