Tacrolimus Topical · larger labeled portfolio than Cannabidiol
SPL labels Tacrolimus Topical + Cannabidiol as minor; Tacrolimus Topical 6 / Cannabidiol 7 in that band.
Mechanism on file: Cannabidiol slows down the process of clearing tacrolimus from your body, which can cause the drug to reach high and potentially harmful levels.
FDA SPL severity: Minor
Tacrolimus Topical + Cannabidiol · SPL mechanism field
Cannabidiol slows down the process of clearing tacrolimus from your body, which can cause the drug to reach high and potentially harmful levels.
Minor band excerpt · Tacrolimus Topical with Cannabidiol
( 2.4 , 5.10 , 7.2 ) Therapeutic drug monitoring and dose reduction for tacrolimus extended-release capsules should be considered when tacrolimus extended-release capsules is co-administered with cannabidiol. 7.3 Cannabidiol The blood levels of tacrolimus may increase upon concomitant use with cannabidiol. When cannabidiol and tacrolimus extended-release capsules are co-administered, closely monitor for an increase in tacrolimus blood levels and for adverse reactions suggestive of tacrolimus toxicity.
Tacrolimus Topical · 25 SPL pairs (broader portfolio than Cannabidiol)
- Caspofungin minor
- Cyclosporine minor
- Methylprednisolone minor
- Midazolam minor
Cannabidiol · 7 minor + 8 total pairs
- Clopidogrel minor
- Digoxin minor
- Rifampin minor
- Theophylline minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.