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What the FDA labels say about taking them together

Tacrolimus and tinidazole

Tinidazole's FDA label of December 27, 2021 names tacrolimus in its drug interactions section; the tacrolimus labels PlainMeds reads (4) do not name tinidazole. The tinidazole label: “Avoid during and up to 3 days after tinidazole therapy Lithium: Monitor serum lithium concentrations Cyclosporine, tacrolimus:”

Check it at the source: the tacrolimus FDA label on DailyMed (effective July 17, 2026, Stellon Biotech Inc.); the tinidazole FDA label on DailyMed (effective December 27, 2021, Mission Pharmacal Company).

What does the tacrolimus label say about tinidazole?

Tacrolimus's label (effective July 17, 2026) and its 3 other brand-application labels do not name tinidazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tacrolimus), Stellon Biotech Inc., effective July 17, 2026 (SPL set 6b89e8a4-9f11-42e3-8e79-fe617e7c461f), via openFDA; the full label on DailyMed

What does the tinidazole label say about tacrolimus?

Tinidazole label, drug interactions

Avoid during and up to 3 days after tinidazole therapy ( 7.1 ) Lithium: Monitor serum lithium concentrations ( 7.1 ) Cyclosporine, tacrolimus:

Source: FDA drug label (Tindamax), Mission Pharmacal Company, effective December 27, 2021 (SPL set a0d01539-8413-4703-94cc-d221918630a1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

33Tacrolimus generic labelers
5Tinidazole generic labelers
TacrolimusTinidazole
Labeled forOrgan transplant rejection, Eczema (atopic dermatitis)n/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.970 per gram 0.1% ointment$2.35 per tablet 500 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?