What the FDA labels say about taking them together
Sunitinib and temsirolimus
Temsirolimus's FDA label of December 26, 2025 names sunitinib in its warnings and precautions section; the sunitinib label PlainMeds reads does not name temsirolimus. The temsirolimus label: “Concomitant use of TORISEL with sunitinib The combination of TORISEL and sunitinib resulted in dose-limiting toxicity.”
Check it at the source: the sunitinib FDA label on DailyMed (effective February 20, 2026, Pfizer Laboratories Div Pfizer Inc); the temsirolimus FDA label on DailyMed (effective December 26, 2025, Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.).
What does the sunitinib label say about temsirolimus?
Sunitinib's label (effective February 20, 2026) does not name temsirolimus in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SUTENT), NDA021938 (Cppi Cv), as published by Pfizer Laboratories Div Pfizer Inc, effective February 20, 2026 (SPL set 43a4d7f8-48ae-4a63-9108-2fa8e3ea9d9c), via openFDA; the full label on DailyMed
What does the temsirolimus label say about sunitinib?
Temsirolimus label, warnings and precautionsConcomitant use of TORISEL with sunitinib The combination of TORISEL and sunitinib resulted in dose-limiting toxicity.
Source: FDA drug label (Torisel), NDA022088 (Pf Prism Cv), as published by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., effective December 26, 2025 (SPL set 95b7dc92-2180-42f1-8699-3c28f609e674), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Sunitinib | Temsirolimus | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once