What the FDA labels say about taking them together
Stiripentol and triazolam
Stiripentol's FDA label of April 27, 2026 names triazolam in its drug interactions section; the triazolam label PlainMeds reads does not name stiripentol. The stiripentol label: “Because of potential drug-drug interactions, consider dose adjustment of CYP1A2 substrates, CYP2B6 substrates, and CYP3A4 substrates, as clinically appropriate, when administered concomitantly with DIACOMIT.”
Check it at the source: the stiripentol FDA label on DailyMed (effective April 27, 2026, BIOCODEX, INC.); the triazolam FDA label on DailyMed (effective July 10, 2026, Mylan Pharmaceuticals Inc.).
What does the stiripentol label say about triazolam?
Stiripentol label, drug interactionsBecause of potential drug-drug interactions, consider dose adjustment of CYP1A2 substrates (e.g., theophylline, caffeine), CYP2B6 substrates (e.g., sertraline, thiotepa), and CYP3A4 substrates (e.g., midazolam, triazolam, quinidine), as clinically appropriate, when administered concomitantly with DIACOMIT.
Source: FDA drug label (Diacomit), BIOCODEX, INC., effective April 27, 2026 (SPL set 58304ba8-9779-4658-811e-94ffe08c3f16), via openFDA; the full label on DailyMed
What does the triazolam label say about stiripentol?
Triazolam's label (effective July 10, 2026) does not name stiripentol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Triazolam), NDA017892 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective July 10, 2026 (SPL set 5add318e-11b9-42f8-b052-0d8cebb32fcf), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Stiripentol | Triazolam | |
|---|---|---|
| Labeled for | n/a | Insomnia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.308 per tablet 0.25 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once