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What the FDA labels say about taking them together

Sotalol and toremifene

Toremifene's FDA label of November 13, 2024 names sotalol in its drug interactions section; the sotalol labels PlainMeds reads (3) do not name toremifene. The toremifene label: “Agents generally accepted to prolong QT interval include Class 1A and Class III antiarrhythmics; certain antipsychotics; certain antidepressants; certain antibiotics; and certain anti-emetics.”

Check it at the source: the sotalol FDA label on DailyMed (effective December 16, 2024, Legacy Pharma USA, Inc.); the toremifene FDA label on DailyMed (effective November 13, 2024, Kyowa Kirin, Inc.).

What does the sotalol label say about toremifene?

Sotalol's label (effective December 16, 2024) and its 2 other brand-application labels do not name toremifene in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (BETAPACE), Legacy Pharma USA, Inc., effective December 16, 2024 (SPL set a6a7702f-36c9-45db-b640-453dc324baee), via openFDA; the full label on DailyMed

What does the toremifene label say about sotalol?

Toremifene label, drug interactions

Agents generally accepted to prolong QT interval include Class 1A (e.g., quinidine, procainamide, disopyramide) and Class III (e.g., amiodarone, sotalol, ibutilide, dofetilide) antiarrhythmics; certain antipsychotics (e.g., thioridazine, haloperidol); certain antidepressants (e.g., venlafaxine, amitriptyline); certain antibiotics (e.g., erythromycin, clarithromycin, levofloxacin, ofloxacin); and certain anti-emetics (e.g., ondansetron, granisetron).

Source: FDA drug label (Fareston), Kyowa Kirin, Inc., effective November 13, 2024 (SPL set 2cab8dd1-3a10-48e6-86ce-0e5275ed49e5), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Sotalol generic labelers
2Toremifene generic labelers
SotalolToremifene
Labeled forAtrial fibrillationBreast cancer
Boxed warningYesYes
Pharmacy cost (NADAC)$0.0707 per tablet 80 mg tablet$19.60 per tablet 60 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?