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What the FDA labels say about taking them together

Somatrogon and somatropin

Somatrogon's FDA label of August 14, 2026 names somatropin in its contraindications section; the somatropin labels PlainMeds reads (4) do not name somatrogon. The somatrogon label: “Increased risk of a second neoplasm in childhood cancer survivors treated with somatropin – in particular meningiomas in patients treated with radiation to the head for their first neoplasm.”

Check it at the source: the somatrogon FDA label on DailyMed (effective August 14, 2026); the somatropin FDA label on DailyMed (effective August 20, 2026, Eli Lilly and Company).

What does the somatrogon label say about somatropin?

Somatrogon label, contraindications

Acute critical illness after open heart surgery, abdominal surgery or multiple accidental trauma, or those with acute respiratory failure due to the risk of increased mortality with somatropin [see Warnings and Precautions (5.1) ].

Somatrogon label, warnings and precautions

Increased risk of a second neoplasm in childhood cancer survivors treated with somatropin – in particular meningiomas in patients treated with radiation to the head for their first neoplasm ( 5.3 ).

Source: FDA drug label (Ngenla), Pfizer Laboratories Div Pfizer Inc, effective August 14, 2026 (SPL set 06dce529-b741-4a1b-8842-3ad77be6e308), via openFDA; the full label on DailyMed

What does the somatropin label say about somatrogon?

Somatropin's label (effective August 20, 2026) and its 3 other brand-application labels do not name somatrogon in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (HUMATROPE), Eli Lilly and Company, effective August 20, 2026 (SPL set a774e1ae-3997-49ee-8b0e-99a2b315d409), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Somatrogon generic labelers
0Somatropin generic labelers
SomatrogonSomatropin
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$752.22 per cartridge 5 mg cartridge
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?