Darunavir · more major-labeled pairs than Sofosbuvir/Velpatasvir
SPL labels Sofosbuvir/Velpatasvir + Darunavir as minor; Sofosbuvir/Velpatasvir 20 / Darunavir 70 in that band.
Mechanism on file: Research indicates that there is no important interaction between these two medications. They do not interfere with each other's levels in the blood.
FDA SPL severity: Minor
Sofosbuvir/Velpatasvir + Darunavir · SPL mechanism field
Research indicates that there is no important interaction between these two medications. They do not interfere with each other's levels in the blood.
Minor band excerpt · Sofosbuvir/Velpatasvir with Darunavir
7.4 Drugs without Clinically Significant Interactions with VOSEVI Based on drug interaction studies conducted with the components of VOSEVI (sofosbuvir, velpatasvir, and/or voxilaprevir) or VOSEVI, no clinically significant drug interactions have been observed with the following drugs [see Clinical Pharmacology (12.3) ]: VOSEVI: cobicistat, darunavir, elvitegravir, emtricitabine, ethinyl estradiol/norgestimate, gemfibrozil, rilpivirine, ritonavir, tenofovir alafenamide, voriconazole Sofosbuvir/velpatasvir: dolutegravir, ketoconazole, raltegravir Sofosbuvir: methadone, tacrolimus
Sofosbuvir/Velpatasvir · 20 minor + 33 total pairs
- Atorvastatin minor
- Bictegravir/Emtricitabine/Tenofovir minor
- Dabigatran minor
- Digoxin minor
Darunavir · 15 major-labeled pairs (vs Sofosbuvir/Velpatasvir's 3)
- Amiodarone minor
- Amitriptyline minor
- Amlodipine minor
- Beclomethasone minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.