What the FDA labels say about taking them together
Sevelamer and tecovirimat
Tecovirimat's FDA label of December 31, 2025 names sevelamer in its drug interactions section; the sevelamer labels PlainMeds reads (2) do not name tecovirimat. The tecovirimat label: “Monitor for signs or symptoms of adverse effects when TPOXX is co-administered with phosphate binders.”
Check it at the source: the sevelamer FDA label on DailyMed (effective November 25, 2025, Sanofi-Aventis U.S. LLC); the tecovirimat FDA label on DailyMed (effective December 31, 2025, SIGA Technologies, Inc.).
What does the sevelamer label say about tecovirimat?
Sevelamer's label (effective November 25, 2025) and its 1 other brand-application label do not name tecovirimat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Sevelamer Carbonate), Sanofi-Aventis U.S. LLC, effective November 25, 2025 (SPL set 3abc32fe-1bfc-4759-8f7c-36095e221b06), via openFDA; the full label on DailyMed
What does the tecovirimat label say about sevelamer?
Tecovirimat label, drug interactionsConcomitant Drug Class/Drug Name: Calcium acetate Lanthanum carbonate Sevelamer carbonate Sucroferric oxyhydroxide; Effect on Concentration a: ↑ tecovirimat; Clinical Effect/Recommendation: Monitor for signs or symptoms of adverse effects when TPOXX is co-administered with phosphate binders [see Overdose ()].
Source: FDA drug label (TPOXX), SIGA Technologies, Inc., effective December 31, 2025 (SPL set fce826ab-4d6a-4139-a2ee-a304a913a253), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Sevelamer | Tecovirimat | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.214 per tablet 800 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once