What the FDA labels say about taking them together
Ketoconazole and saxagliptin
Saxagliptin's FDA label of January 27, 2026 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name saxagliptin. The saxagliptin label: “Strong CYP3A4/5 inhibitors (e.g., ketoconazole): Coadministration with saxagliptin significantly increases saxagliptin concentrations.”
Check it at the source: the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC); the saxagliptin FDA label on DailyMed (effective January 27, 2026, Glenmark Pharmaceuticals Inc., USA).
What does the ketoconazole label say about saxagliptin?
Ketoconazole's label (effective January 28, 2026) does not name saxagliptin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed
What does the saxagliptin label say about ketoconazole?
Saxagliptin label, drug interactionsStrong CYP3A4/5 inhibitors (e.g., ketoconazole): Coadministration with saxagliptin significantly increases saxagliptin concentrations.
Source: FDA drug label (SAXAGLIPTIN), Glenmark Pharmaceuticals Inc., USA, effective January 27, 2026 (SPL set e286ffd4-c598-47fb-af06-2e15f7e6f99f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ketoconazole | Saxagliptin | |
|---|---|---|
| Labeled for | Fungal infections | Type 2 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.249 per gram 2% cream | $1.04 per tablet 5 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once