What the FDA labels say about taking them together
Meperidine and safinamide
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the meperidine FDA label on DailyMed (effective November 29, 2025, EPIC PHARMA, LLC); safinamide labels on DailyMed.
What does the meperidine label say about safinamide?
Meperidine's label (effective November 29, 2025) and its 1 other brand-application label do not name safinamide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Meperidine Hydrochloride), EPIC PHARMA, LLC, effective November 29, 2025 (SPL set fae5cc34-5917-4445-9516-25f97ffca8db), via openFDA; the full label on DailyMed
What does the safinamide label say about meperidine?
Safinamide's label (effective ) does not name meperidine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label, labeler not named, effective (SPL set ), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Meperidine | Safinamide | |
|---|---|---|
| Labeled for | Pain | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.157 per mL 50 mg/5 mL solution | $36.33 per tablet 100 mg tablet |
| Shortage now | Listed; available | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once