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What the FDA labels say about taking them together

Rosuvastatin and voclosporin

Voclosporin's FDA label of August 25, 2026 names rosuvastatin in its drug interactions section; the rosuvastatin labels PlainMeds reads (2) do not name voclosporin. The voclosporin label: “Monitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing …”

Check it at the source: the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).

What does the rosuvastatin label say about voclosporin?

Rosuvastatin's label (effective September 4, 2026) and its 1 other brand-application label do not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed

What does the voclosporin label say about rosuvastatin?

Voclosporin label, drug interactions

Monitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates (e.g., simvastatin, atorvastatin, pravastatin, rosuvastatin, pitavastatin, fluvastatin) are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing information.

Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

45Rosuvastatin generic labelers
0Voclosporin generic labelers
RosuvastatinVoclosporin
Labeled forHeart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke preventionn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0692 per tablet 40 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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