What the FDA labels say about taking them together
Rosuvastatin and teriflunomide
Rosuvastatin's FDA label of September 4, 2026 names teriflunomide in its drug interactions section, and teriflunomide's label names rosuvastatin too. The rosuvastatin label: “Mechanism and Clinical Effect (s): Teriflunomide increased rosuvastatin exposure more than 2.5-fold.”
Check it at the source: the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.); the teriflunomide FDA label on DailyMed (effective February 20, 2026, Genzyme Corporation).
What does the rosuvastatin label say about teriflunomide?
Rosuvastatin label, drug interactionsMechanism and Clinical Effect (s): Teriflunomide increased rosuvastatin exposure more than 2.5-fold.
Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed
What does the teriflunomide label say about rosuvastatin?
Teriflunomide label, drug interactionsThe dose of rosuvastatin should not exceed 10 mg once daily in patients taking AUBAGIO. ( 7 ) Effect of AUBAGIO on CYP2C8 Substrates Teriflunomide is an inhibitor of CYP2C8 in vivo.
Source: FDA drug label (Aubagio), NDA202992 (Sanofi Aventis Us), as published by Genzyme Corporation, effective February 20, 2026 (SPL set 4650d12c-b9c8-4525-b07f-a2d773eca155), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Rosuvastatin | Teriflunomide | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke prevention | Multiple sclerosis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0692 per tablet 40 mg tablet | $0.233 per tablet 14 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once