What the FDA labels say about taking them together
Rosuvastatin and tafamidis
Rosuvastatin's FDA label of September 4, 2026 names tafamidis in its drug interactions section, and tafamidis's label names rosuvastatin too. The rosuvastatin label: “Tafamidis Prevention or Management: Avoid concomitant use of tafamidis with CRESTOR.”
Check it at the source: the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.); the tafamidis FDA label on DailyMed (effective May 12, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the rosuvastatin label say about tafamidis?
Rosuvastatin label, drug interactionsTafamidis Prevention or Management: Avoid concomitant use of tafamidis with rosuvastatin.
Source: FDA drug label (Crestor, NDA021366), AstraZeneca Pharmaceuticals LP, effective April 29, 2026 (SPL set 325a5d0e-9a72-4015-9fcd-1655fb504cee), via openFDA
Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed
What does the tafamidis label say about rosuvastatin?
Tafamidis label, drug interactionsCoadministration of tafamidis and drugs that are BCRP substrates may increase the exposure of substrates of this transporter (e.g., methotrexate, rosuvastatin, imatinib) and the risk of the substrate-related toxicities.
Source: FDA drug label (Vyndaqel), NDA211996 (Foldrx Pharms), as published by Pfizer Laboratories Div Pfizer Inc, effective May 12, 2026 (SPL set 1b4121ee-a733-4456-a917-be2603477839), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Rosuvastatin | Tafamidis | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke prevention | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0692 per tablet 40 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once