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What the FDA labels say about taking them together

Metoclopramide and ropinirole

Metoclopramide's FDA label of May 18, 2026 names ropinirole in its drug interactions section, and ropinirole's label names metoclopramide too. The ropinirole label: “Dopamine antagonists: May reduce efficacy of ropinirole.”

Check it at the source: the metoclopramide FDA label on DailyMed (effective May 18, 2026, ANI Pharmaceuticals, Inc.); the ropinirole FDA label on DailyMed (effective January 16, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the metoclopramide label say about ropinirole?

Metoclopramide label, drug interactions

Examples; apomorphine, bromocriptine, cabergoline, levodopa, pramipexole, ropinirole, and rotigotine

Source: FDA drug label (Metoclopramide), NDA017854 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective May 18, 2026 (SPL set 797aad80-0597-42f8-99d5-39de180c3b5a), via openFDA; the full label on DailyMed

What does the ropinirole label say about metoclopramide?

Ropinirole label, drug interactions

Dopamine antagonists (e.g., neuroleptics, metoclopramide): May reduce efficacy of ropinirole.

Source: FDA drug label (ropinirole), Glenmark Pharmaceuticals Inc., USA, effective January 16, 2026 (SPL set 85971b31-6f7d-421c-bf3c-5b33f3c1e781), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

39Metoclopramide generic labelers
26Ropinirole generic labelers
MetoclopramideRopinirole
Labeled forAcid reflux and ulcers, Nausea and vomitingParkinson's disease
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0439 per tablet 10 mg tablet$0.046 per tablet 0.25 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?