What the FDA labels say about taking them together
Ritonavir and umeclidinium/vilanterol
Umeclidinium/vilanterol's FDA label of June 2, 2023 names ritonavir in its warnings and precautions section; the ritonavir label PlainMeds reads does not name umeclidinium/vilanterol. The umeclidinium/vilanterol label: “Interactions with Strong Cytochrome P450 3A4 Inhibitors Caution should be exercised when considering the coadministration of ANORO ELLIPTA with ketoconazole and other known strong cytochrome P450 3A4 (CYP3A4) inhibitors …”
Check it at the source: the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.); the umeclidinium/vilanterol FDA label on DailyMed (effective June 2, 2023, GlaxoSmithKline LLC).
What does the ritonavir label say about umeclidinium/vilanterol?
Ritonavir's label (effective July 23, 2026) does not name umeclidinium/vilanterol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
What does the umeclidinium/vilanterol label say about ritonavir?
Umeclidinium/vilanterol label, warnings and precautionsInteractions with Strong Cytochrome P450 3A4 Inhibitors Caution should be exercised when considering the coadministration of ANORO ELLIPTA with ketoconazole and other known strong cytochrome P450 3A4 (CYP3A4) inhibitors (including, but not limited to, ritonavir, clarithromycin, conivaptan, indinavir, itraconazole, lopinavir, nefazodone, nelfinavir, saquinavir, telithromycin, troleandomycin, voriconazole) because increased cardiovascular adverse effects may occur [see Drug Interactions ( 7.1 ), Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Anoro Ellipta), GlaxoSmithKline LLC, effective June 2, 2023 (SPL set 2dbd0671-c565-40c5-bf0f-e324db26799c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ritonavir | Umeclidinium/vilanterol | |
|---|---|---|
| Labeled for | HIV | COPD |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.607 per tablet 100 mg tablet | $4.95 per inhaler 62.5-25 mcg inhaler |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once