What the FDA labels say about taking them together
Ritonavir and trabectedin
Trabectedin's FDA label (Yondelis) of January 6, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name trabectedin. The trabectedin label: “Avoid using strong CYP3A inhibitors in patients taking YONDELIS.”
Check it at the source: the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.); the trabectedin FDA label on DailyMed (effective June 29, 2026, Apotex Corp.).
What does the ritonavir label say about trabectedin?
Ritonavir's label (effective July 23, 2026) does not name trabectedin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
What does the trabectedin label say about ritonavir?
Yondelis label (Janssen Products, LP, January 6, 2026), drug interactionsAvoid using strong CYP3A inhibitors (e.g., oral ketoconazole, itraconazole, posaconazole, voriconazole, clarithromycin, telithromycin, indinavir, lopinavir, ritonavir, boceprevir, nelfinavir, saquinavir, telaprevir, nefazodone, conivaptan) in patients taking YONDELIS.
Source: FDA drug label (Yondelis, NDA207953), Janssen Products, LP, effective January 6, 2026 (SPL set 472bd78e-be17-4b9d-90f4-9482c3aec9ff), via openFDA
Source: FDA drug label (EVDI), Apotex Corp., effective June 29, 2026 (SPL set c1d50f5c-4202-27f3-4798-a9708114ddea), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ritonavir | Trabectedin | |
|---|---|---|
| Labeled for | HIV | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.607 per tablet 100 mg tablet | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once