Skip to main content

What the FDA labels say about taking them together

Ritonavir and saxagliptin

Saxagliptin's FDA label of January 27, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name saxagliptin. The saxagliptin label: “Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors.”

Check it at the source: the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.); the saxagliptin FDA label on DailyMed (effective January 27, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the ritonavir label say about saxagliptin?

Ritonavir's label (effective July 23, 2026) does not name saxagliptin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

What does the saxagliptin label say about ritonavir?

Saxagliptin label, drug interactions

Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors (e.g., atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin).

Source: FDA drug label (SAXAGLIPTIN), Glenmark Pharmaceuticals Inc., USA, effective January 27, 2026 (SPL set e286ffd4-c598-47fb-af06-2e15f7e6f99f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

7Ritonavir generic labelers
3Saxagliptin generic labelers
RitonavirSaxagliptin
Labeled forHIVType 2 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)$0.607 per tablet 100 mg tablet$1.04 per tablet 5 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?