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What the FDA labels say about taking them together

Rifampin and ulipristal

Ulipristal's FDA label of July 20, 2026 names rifampin in its warnings and precautions section; the rifampin label PlainMeds reads does not name ulipristal. The ulipristal label: “CYP3A4 Inducers A CYP3A4 inducer, rifampin, decreases the plasma concentration of ella significantly.”

Check it at the source: the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.); the ulipristal FDA label on DailyMed (effective July 20, 2026, PMI Branded Pharmaceuticals, Inc.).

What does the rifampin label say about ulipristal?

Rifampin's label (effective February 11, 2026) does not name ulipristal in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed

What does the ulipristal label say about rifampin?

Ulipristal label, warnings and precautions

CYP3A4 Inducers A CYP3A4 inducer, rifampin, decreases the plasma concentration of ella significantly.

Source: FDA drug label (Ella), PMI Branded Pharmaceuticals, Inc., effective July 20, 2026 (SPL set 2bf93d23-cddd-4613-9066-5b5fa090404b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Rifampin generic labelers
0Ulipristal generic labelers
RifampinUlipristal
Labeled forn/aBirth control
Boxed warningNoNo
Pharmacy cost (NADAC)$0.679 per capsule 300 mg capsule$37.10 per tablet 30 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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