What the FDA labels say about taking them together
Rifampin and triamcinolone
Triamcinolone's FDA label (Triesence) of June 5, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name triamcinolone. The triamcinolone label: “CYP 3A4 inducers; Drugs which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of corticosteroids and require that the dosage of corticosteroid be increased.”
Check it at the source: the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.); the triamcinolone FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).
What does the rifampin label say about triamcinolone?
Rifampin's label (effective February 11, 2026) does not name triamcinolone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
What does the triamcinolone label say about rifampin?
Triesence label (Harrow Eye, LLC, June 5, 2026), drug interactionsCYP 3A4 inducers (e.g., barbiturates, phenytoin, carbamazepine, and rifampin): Drugs, such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of corticosteroid and require that the dosage of corticosteroid be increased.
Source: FDA drug label (Triesence, NDA022048), Harrow Eye, LLC, effective June 5, 2026 (SPL set 2267978c-72ad-9229-e063-6394a90a09d0), via openFDA
Source: FDA drug label (Zilretta, NDA208845), Pacira Pharmaceuticals, Inc., effective June 3, 2026 (SPL set cd5c4673-21f2-4126-9556-da847b3a228b), via openFDA
Source: FDA drug label (triamcinolone acetonide), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set 92a1ded0-8e1a-4994-9c8a-89e84fc85c94), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Rifampin | Triamcinolone | |
|---|---|---|
| Labeled for | n/a | Asthma, Eczema (atopic dermatitis), Anemia, Leukemia, lymphoma and myeloma, Allergies, Fever, Pain, Osteoarthritis |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.679 per capsule 300 mg capsule | $0.0452 per gram 0.1% cream |
| Shortage now | In shortage | Listed; available |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once