What the FDA labels say about taking them together
Rifampin and ritlecitinib
Ritlecitinib's FDA label of June 17, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name ritlecitinib. The ritlecitinib label: “Clinical Impact; Concomitant use of strong CYP3A inducer (e.g., rifampin) may decrease AUC and C max of ritlecitinib, which may result in loss of or reduced clinical response.”
Check it at the source: the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.); the ritlecitinib FDA label on DailyMed (effective June 17, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the rifampin label say about ritlecitinib?
Rifampin's label (effective February 11, 2026) does not name ritlecitinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
What does the ritlecitinib label say about rifampin?
Ritlecitinib label, drug interactionsClinical Impact; Concomitant use of strong CYP3A inducer (e.g., rifampin) may decrease AUC and C max of ritlecitinib [see ], which may result in loss of or reduced clinical response.
Source: FDA drug label (Litfulo), Pfizer Laboratories Div Pfizer Inc, effective June 17, 2026 (SPL set 6b2f9446-fb23-4741-b73a-5a2f993733c3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Rifampin | Ritlecitinib | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.679 per capsule 300 mg capsule | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once