What the FDA labels say about taking them together
Octreotide and repaglinide
Repaglinide's FDA label of May 2, 2025 names octreotide in its drug interactions section; the octreotide labels PlainMeds reads (4) do not name repaglinide. The repaglinide label: “… pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics.”
Check it at the source: the octreotide FDA label on DailyMed (effective July 22, 2026, Novartis Pharmaceuticals Corporation); the repaglinide FDA label on DailyMed (effective May 2, 2025, Chartwell RX, LLC).
What does the octreotide label say about repaglinide?
Octreotide's label (effective July 22, 2026) and its 3 other brand-application labels do not name repaglinide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Sandostatin), Novartis Pharmaceuticals Corporation, effective July 22, 2026 (SPL set 4e2c9856-1836-49f0-9472-4dbeeb408f39), via openFDA; the full label on DailyMed
What does the repaglinide label say about octreotide?
Repaglinide label, drug interactionsDrugs That May Increase the Risk of Hypoglycemia Intervention: Repaglinide tablets dose reductions and increased frequency of glucose monitoring may be required when co-administered. Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics.
Source: FDA drug label (Repaglinide), Chartwell RX, LLC, effective May 2, 2025 (SPL set cb995e92-295e-4638-a064-978211f5afe1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Octreotide | Repaglinide | |
|---|---|---|
| Labeled for | Diarrhea | Type 2 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $2.53 per mL 100 mcg/mL vial | $0.0987 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once