What the FDA labels say about taking them together
Repaglinide and somatropin
Repaglinide's FDA label of May 2, 2025 names somatropin in its drug interactions section; the somatropin labels PlainMeds reads (4) do not name repaglinide. The repaglinide label: “… niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic agents, and thyroid hormones.”
Check it at the source: the repaglinide FDA label on DailyMed (effective May 2, 2025, Chartwell RX, LLC); the somatropin FDA label on DailyMed (effective August 20, 2026, Eli Lilly and Company).
What does the repaglinide label say about somatropin?
Repaglinide label, drug interactionsDrugs That May Decrease the Blood Glucose Lowering Effect of Repaglinide Tablets Intervention: Repaglinide tablets dose increases and increased frequency of glucose monitoring may be required when co-administered. Examples: Atypical antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones.
Source: FDA drug label (Repaglinide), Chartwell RX, LLC, effective May 2, 2025 (SPL set cb995e92-295e-4638-a064-978211f5afe1), via openFDA; the full label on DailyMed
What does the somatropin label say about repaglinide?
Somatropin's label (effective August 20, 2026) and its 3 other brand-application labels do not name repaglinide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (HUMATROPE), Eli Lilly and Company, effective August 20, 2026 (SPL set a774e1ae-3997-49ee-8b0e-99a2b315d409), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Repaglinide | Somatropin | |
|---|---|---|
| Labeled for | Type 2 diabetes | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0987 per tablet 1 mg tablet | $752.22 per cartridge 5 mg cartridge |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once