What the FDA labels say about taking them together
Clonidine and repaglinide
Repaglinide's FDA label of May 2, 2025 names clonidine in its drug interactions section; the clonidine labels PlainMeds reads (4) do not name repaglinide. The repaglinide label: “… repaglinide tablets is co-administered with these drugs. Examples: beta-blockers, clonidine, guanethidine, and reserpine”
Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the repaglinide FDA label on DailyMed (effective May 2, 2025, Chartwell RX, LLC).
What does the clonidine label say about repaglinide?
Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name repaglinide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
What does the repaglinide label say about clonidine?
Repaglinide label, drug interactionsDrugs That May Blunt Signs and Symptoms of Hypoglycemia Intervention: Increased frequency of glucose monitoring may be required when repaglinide tablets is co-administered with these drugs. Examples: beta-blockers, clonidine, guanethidine, and reserpine
Source: FDA drug label (Repaglinide), Chartwell RX, LLC, effective May 2, 2025 (SPL set cb995e92-295e-4638-a064-978211f5afe1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clonidine | Repaglinide | |
|---|---|---|
| Labeled for | High blood pressure, ADHD, Pain | Type 2 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0241 per tablet 0.1 mg tablet | $0.0987 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once