What the FDA labels say about taking them together
Quizartinib and tacrolimus
Quizartinib's FDA label of April 16, 2026 names tacrolimus in its drug interactions section; the tacrolimus labels PlainMeds reads (4) do not name quizartinib. The quizartinib label: “… pentamidine, doxycycline, moxifloxacin, atovaquone, prochlorperazine, and tacrolimus.”
Check it at the source: the quizartinib FDA label on DailyMed (effective April 16, 2026, Daiichi Sankyo Inc.); the tacrolimus FDA label on DailyMed (effective July 17, 2026, Stellon Biotech Inc.).
What does the quizartinib label say about tacrolimus?
Quizartinib label, drug interactionsQT Interval Prolonging Drugs Clinical Impact VANFLYTA prolongs the QT/QTc interval. Coadministration of VANFLYTA with other drugs that prolong the QT interval may further increase the incidence of QT prolongation [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2) ]. Prevention or Management Monitor patients more frequently with ECG if co-administration of VANFLYTA with drugs known to prolong the QT interval is required. Examples of QT prolonging drugs include but are not limited to antifungal azoles, ondansetron, granisetron, azithromycin, pentamidine, doxycycline, moxifloxacin, atovaquone, prochlorperazine, and tacrolimus.
Source: FDA drug label (VANFLYTA), Daiichi Sankyo Inc., effective April 16, 2026 (SPL set 29cdbcfe-497d-4e78-bb7b-2d4acafe8e86), via openFDA; the full label on DailyMed
What does the tacrolimus label say about quizartinib?
Tacrolimus's label (effective July 17, 2026) and its 3 other brand-application labels do not name quizartinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tacrolimus), Stellon Biotech Inc., effective July 17, 2026 (SPL set 6b89e8a4-9f11-42e3-8e79-fe617e7c461f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Quizartinib | Tacrolimus | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Organ transplant rejection, Eczema (atopic dermatitis) |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.970 per gram 0.1% ointment |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once