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What the FDA labels say about taking them together

Quinidine and stiripentol

Stiripentol's FDA label of April 27, 2026 names quinidine in its drug interactions section; the quinidine label PlainMeds reads does not name stiripentol. The stiripentol label: “Because of potential drug-drug interactions, consider dose adjustment of CYP1A2 substrates, CYP2B6 substrates, and CYP3A4 substrates, as clinically appropriate, when administered concomitantly with DIACOMIT.”

Check it at the source: the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.); the stiripentol FDA label on DailyMed (effective April 27, 2026, BIOCODEX, INC.).

What does the quinidine label say about stiripentol?

Quinidine's label (effective February 1, 2018) does not name stiripentol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed

What does the stiripentol label say about quinidine?

Stiripentol label, drug interactions

Because of potential drug-drug interactions, consider dose adjustment of CYP1A2 substrates (e.g., theophylline, caffeine), CYP2B6 substrates (e.g., sertraline, thiotepa), and CYP3A4 substrates (e.g., midazolam, triazolam, quinidine), as clinically appropriate, when administered concomitantly with DIACOMIT.

Source: FDA drug label (Diacomit), BIOCODEX, INC., effective April 27, 2026 (SPL set 58304ba8-9779-4658-811e-94ffe08c3f16), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Quinidine generic labelers
0Stiripentol generic labelers
QuinidineStiripentol
Labeled forAtrial fibrillationn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$4.92 per tablet 324 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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