What the FDA labels say about taking them together
Quetiapine and ritonavir
Quetiapine's FDA label of April 10, 2026 names ritonavir in its drug interactions section, and ritonavir's label names quetiapine too. The ritonavir label: “Consider alternative antiretroviral therapy to avoid increases in quetiapine exposures.”
Check it at the source: the quetiapine FDA label on DailyMed (effective April 10, 2026, H2-Pharma, LLC); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the quetiapine label say about ritonavir?
Quetiapine label, drug interactionsConcomitant use of strong CYP3A4 inhibitors: Reduce quetiapine dose to one sixth when coadministered with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
Source: FDA drug label (SEROQUEL), NDA020639 (Cheplapharm), as published by H2-Pharma, LLC, effective April 10, 2026 (SPL set 8ae62aaf-f8c5-417f-baac-0098369ca322), via openFDA; the full label on DailyMed
What does the ritonavir label say about quetiapine?
Ritonavir label, drug interactionsConsider alternative antiretroviral therapy to avoid increases in quetiapine exposures.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Which combination products and biosimilars carry the same label text?
Their labels quote the same sentences for their ingredient; each has its own page with its own label dates.
Both medicines on the record
| Quetiapine | Ritonavir | |
|---|---|---|
| Labeled for | Schizophrenia, Bipolar disorder, Depression | HIV |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.127 per tablet 300 mg tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once