What the FDA labels say about taking them together
Prazosin and stiripentol
Stiripentol's FDA label of April 27, 2026 names prazosin in its drug interactions section; the prazosin label PlainMeds reads does not name stiripentol. The stiripentol label: “Because of potential inhibition of enzyme/transporter activity, consider a reduction in dosage of substrates of CYP2C8, CYP2C19, P-gp (e.g., carbamazepine), and BCRP, if adverse reactions are experienced when …”
Check it at the source: the prazosin FDA label on DailyMed (effective March 6, 2026, Prasco Laboratories); the stiripentol FDA label on DailyMed (effective April 27, 2026, BIOCODEX, INC.).
What does the prazosin label say about stiripentol?
Prazosin's label (effective March 6, 2026) does not name stiripentol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Prazosin Hydrochloride), NDA017442 (Pfizer), as published by Prasco Laboratories, effective March 6, 2026 (SPL set cbe89216-7dea-43d7-b12e-44ccfb69af3d), via openFDA; the full label on DailyMed
What does the stiripentol label say about prazosin?
Stiripentol label, drug interactionsBecause of potential inhibition of enzyme/transporter activity, consider a reduction in dosage of substrates of CYP2C8, CYP2C19 (e.g., diazepam, clopidogrel), P-gp (e.g., carbamazepine), and BCRP (e.g., methotrexate, prazosin, glyburide), if adverse reactions are experienced when administered concomitantly with DIACOMIT.
Source: FDA drug label (Diacomit), BIOCODEX, INC., effective April 27, 2026 (SPL set 58304ba8-9779-4658-811e-94ffe08c3f16), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Prazosin | Stiripentol | |
|---|---|---|
| Labeled for | High blood pressure | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0842 per capsule 1 mg capsule | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once