What the FDA labels say about taking them together
Praziquantel and ritonavir
Praziquantel's FDA label of March 2, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name praziquantel. The praziquantel label: “… inhibitors), for example, cimetidine, ketoconazole, itraconazole, erythromycin, and ritonavir may increase plasma concentrations of praziquantel.”
Check it at the source: the praziquantel FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the praziquantel label say about ritonavir?
Praziquantel label, drug interactionsCYP450 inhibitors Concomitant administration of drugs that decrease the activity of drug metabolizing liver enzymes (CYP450 inhibitors), for example, cimetidine, ketoconazole, itraconazole, erythromycin, and ritonavir may increase plasma concentrations of praziquantel.
Source: FDA drug label (Biltricide), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set 34ce1cdd-648e-4f1e-8512-bf3d4cc22eb9), via openFDA; the full label on DailyMed
What does the ritonavir label say about praziquantel?
Ritonavir's label (effective July 23, 2026) does not name praziquantel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Praziquantel | Ritonavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $53.25 per tablet 600 mg tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once