What the FDA labels say about taking them together
Pravastatin and voclosporin
Voclosporin's FDA label of August 25, 2026 names pravastatin in its drug interactions section; the pravastatin label PlainMeds reads does not name voclosporin. The voclosporin label: “Monitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing …”
Check it at the source: the pravastatin FDA label on DailyMed (effective July 31, 2026, Apotex Corp.); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).
What does the pravastatin label say about voclosporin?
Pravastatin's label (effective July 31, 2026) does not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (PRAVASTATIN SODIUM), Apotex Corp., effective July 31, 2026 (SPL set dcf45e4f-b46e-6fbb-b67a-2ff619ab1780), via openFDA; the full label on DailyMed
What does the voclosporin label say about pravastatin?
Voclosporin label, drug interactionsMonitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates (e.g., simvastatin, atorvastatin, pravastatin, rosuvastatin, pitavastatin, fluvastatin) are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing information.
Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pravastatin | Voclosporin | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease, High cholesterol, High triglycerides | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.058 per tablet 20 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once