What the FDA labels say about taking them together
Pralidoxime and succinylcholine
Pralidoxime's FDA label of April 1, 2026 names succinylcholine in its drug interactions section; the succinylcholine labels PlainMeds reads (2) do not name pralidoxime.
Check it at the source: the pralidoxime FDA label on DailyMed (effective April 1, 2026, Baxter Healthcare Corporation); the succinylcholine FDA label on DailyMed (effective August 18, 2026, Hospira, Inc.).
What does the pralidoxime label say about succinylcholine?
Pralidoxime label, drug interactionsProlonged paralysis has been reported in patients when succinylcholine is given with drugs having anticholinesterase activity; therefore, it should be used with caution.
Source: FDA drug label (Protopam Chloride), Baxter Healthcare Corporation, effective April 1, 2026 (SPL set 2741d8fd-51c2-46be-880b-99f2b20a6137), via openFDA; the full label on DailyMed
What does the succinylcholine label say about pralidoxime?
Succinylcholine's label (effective August 18, 2026) and its 1 other brand-application label do not name pralidoxime in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (QUELICIN), Hospira, Inc., effective August 18, 2026 (SPL set fb08161e-7711-406d-e7b3-ea4515c07983), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pralidoxime | Succinylcholine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once