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What the FDA labels say about taking them together

Aliskiren and potassium citrate

Potassium citrate's FDA label of December 2, 2021 names aliskiren in its drug interactions section; the aliskiren label PlainMeds reads does not name potassium citrate.

Check it at the source: the aliskiren FDA label on DailyMed (effective March 7, 2024, LXO US Inc.); the potassium citrate FDA label on DailyMed (effective December 2, 2021, Mission Pharmacal Company).

What does the aliskiren label say about potassium citrate?

Aliskiren's label (effective March 7, 2024) does not name potassium citrate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tekturna), NDA021985 (Lxo Ireland), as published by LXO US Inc., effective March 7, 2024 (SPL set 3dd61fa5-1620-4ebf-bbdb-ede29b92fce2), via openFDA; the full label on DailyMed

What does the potassium citrate label say about aliskiren?

Potassium citrate label, drug interactions

Drugs that inhibit the renin-angiotensin-aldosterone system (RAAS) including angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), spironolactone, eplerenone, or aliskiren produce potassium retention by inhibiting aldosterone production.

Source: FDA drug label (UROCIT-K), Mission Pharmacal Company, effective December 2, 2021 (SPL set 72cdea1b-2240-41db-987d-86d5c6aaa978), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Aliskiren generic labelers
12Potassium citrate generic labelers
AliskirenPotassium citrate
Labeled forHigh blood pressuren/a
Boxed warningYesNo
Pharmacy cost (NADAC)$3.94 per tablet 150 mg tablet$0.175 per tablet 10 mEq tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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