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What the FDA labels say about taking them together

Glipizide and posaconazole

Posaconazole's FDA label of August 3, 2026 names glipizide in its drug interactions section; the glipizide labels PlainMeds reads (2) do not name posaconazole. The posaconazole label: “However, glucose concentrations decrease in some patients concomitantly administered posaconazole and glipizide.”

Check it at the source: the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited); the posaconazole FDA label on DailyMed (effective August 3, 2026, Aurobindo Pharma Limited).

What does the glipizide label say about posaconazole?

Glipizide's label (effective January 8, 2026) and its 1 other brand-application label do not name posaconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed

What does the posaconazole label say about glipizide?

Posaconazole label, drug interactions

However, glucose concentrations decrease in some patients concomitantly administered posaconazole and glipizide.

Source: FDA drug label (POSACONAZOLE), Aurobindo Pharma Limited, effective August 3, 2026 (SPL set f8a26673-261c-4e8e-b1e1-9e23aaf7f285), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

31Glipizide generic labelers
27Posaconazole generic labelers
GlipizidePosaconazole
Labeled forType 2 diabetesFungal infections
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0339 per tablet 5 mg tablet$2.03 per tablet 100 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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