What the FDA labels say about taking them together
Pomalidomide and thalidomide
Pomalidomide's FDA label of February 26, 2025 names thalidomide in its boxed warning section; the thalidomide label PlainMeds reads does not name pomalidomide.
Check it at the source: the pomalidomide FDA label on DailyMed (effective February 26, 2025, Celgene Corporation); the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).
What does the pomalidomide label say about thalidomide?
Pomalidomide label, boxed warningThalidomide is a known human teratogen that causes severe life-threatening birth defects ( 4 , 5.1 , 8.1 ).
Pomalidomide label, warnings and precautionsThalidomide is a known human teratogen that causes severe birth defects or embryo-fetal death [see Use in Specific Populations (8.1) ].
Source: FDA drug label (Pomalyst), NDA204026 (Bristol), as published by Celgene Corporation, effective February 26, 2025 (SPL set 2b25ef01-5c9e-11e1-b86c-0800200c9a66), via openFDA; the full label on DailyMed
What does the thalidomide label say about pomalidomide?
Thalidomide's label (effective March 24, 2023) does not name pomalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pomalidomide | Thalidomide | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once