What the FDA labels say about taking them together
Pimozide and quinine
Quinine's FDA label of November 9, 2023 names pimozide in its drug interactions (prescription label) section; the pimozide label PlainMeds reads does not name quinine. The quinine label: “The concurrent use of quinine sulfate with astemizole and other CYP3A4 substrates with QT prolongation potential should also be avoided.”
Check it at the source: the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC); the quinine FDA label on DailyMed (effective November 9, 2023).
What does the pimozide label say about quinine?
Pimozide's label (effective August 12, 2026) does not name quinine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed
What does the quinine label say about pimozide?
Quinine label, drug interactions (prescription label)The concurrent use of quinine sulfate with astemizole and other CYP3A4 substrates with QT prolongation potential (e.g., cisapride, terfenadine, halofantrine, pimozide and quinidine ) should also be avoided [see WARNINGS AND PRECAUTIONS ( 5.3 )].
Quinine label, warnings and precautions (prescription label)Quinine may inhibit the metabolism of certain drugs that are CYP3A4 substrates and are known to cause QT prolongation, e.g., astemizole, cisapride, terfenadine, pimozide, halofantrine and quinidine.
Source: FDA drug label (Chininum sulphuricum), Boiron, effective November 9, 2023 (SPL set 33885950-2a55-11e7-8288-424c58303031), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pimozide | Quinine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.23 per tablet 1 mg tablet | $0.698 per capsule 324 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once