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What the FDA labels say about taking them together

Erythromycin and pimecrolimus

Pimecrolimus's FDA label of April 30, 2026 names erythromycin in its drug interactions section; the erythromycin labels PlainMeds reads (4) do not name pimecrolimus.

Check it at the source: the erythromycin FDA label on DailyMed (effective August 1, 2024, Teva Pharmaceuticals USA, Inc.); the pimecrolimus FDA label on DailyMed (effective April 30, 2026, Oceanside Pharmaceuticals).

What does the erythromycin label say about pimecrolimus?

Erythromycin's label (effective August 1, 2024) and its 3 other brand-application labels do not name pimecrolimus in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Erythromycin), Teva Pharmaceuticals USA, Inc., effective August 1, 2024 (SPL set 75a0bd5a-d09f-483b-bfd8-f8343b149eb2), via openFDA; the full label on DailyMed

What does the pimecrolimus label say about erythromycin?

Pimecrolimus label, drug interactions

Some examples of such drugs are erythromycin, itraconazole, ketoconazole, fluconazole, calcium channel blockers and cimetidine.

Source: FDA drug label (Pimecrolimus), NDA021302 (Bausch), as published by Oceanside Pharmaceuticals, effective April 30, 2026 (SPL set 6601e43e-ce7d-446a-8568-8e7b24b86f06), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

38Erythromycin generic labelers
2Pimecrolimus generic labelers
ErythromycinPimecrolimus
Labeled forBacterial infections, AcneEczema (atopic dermatitis)
Boxed warningNoYes
Pharmacy cost (NADAC)$1.96 per tablet 250 mg tablet$3.31 per gram 1% cream
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?