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What the FDA labels say about taking them together

Pilocarpine and tropicamide

Tropicamide's FDA label of September 1, 2023 names pilocarpine in its drug interactions section; the pilocarpine labels PlainMeds reads (3) do not name tropicamide.

Check it at the source: the pilocarpine FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the tropicamide FDA label on DailyMed (effective September 1, 2023, Bausch & Lomb Incorporated).

What does the pilocarpine label say about tropicamide?

Pilocarpine's label (effective December 5, 2024) and its 2 other brand-application labels do not name tropicamide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Salagen), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set 62eda83d-d043-4c7e-8fcf-75d05efbf35b), via openFDA; the full label on DailyMed

What does the tropicamide label say about pilocarpine?

Tropicamide label, drug interactions

Drug Interactions Tropicamide may interfere with the antihypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.

Source: FDA drug label (Tropicamide), Bausch & Lomb Incorporated, effective September 1, 2023 (SPL set 892b78c8-36bc-47d3-850e-502899b48fb9), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

7Pilocarpine generic labelers
5Tropicamide generic labelers
PilocarpineTropicamide
Labeled forGlaucoman/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.338 per tablet 5 mg tablet$0.552 per mL 1% eye drops
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?