What the FDA labels say about taking them together
Pentoxifylline and pramlintide
Pramlintide's FDA label of December 18, 2019 names pentoxifylline in its drug interactions section; the pentoxifylline label PlainMeds reads does not name pramlintide. The pramlintide label: “… inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, salicylates, somatostatin analogs, and sulfonamide antibiotics.”
Check it at the source: the pentoxifylline FDA label on DailyMed (effective May 15, 2026, Rising Pharma Holdings, Inc.); the pramlintide FDA label on DailyMed (effective December 18, 2019, AstraZeneca Pharmaceuticals LP).
What does the pentoxifylline label say about pramlintide?
Pentoxifylline's label (effective May 15, 2026) does not name pramlintide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pentoxifylline), Rising Pharma Holdings, Inc., effective May 15, 2026 (SPL set cd840a2c-2a0e-4b2b-84ff-a0406bb6fa37), via openFDA; the full label on DailyMed
What does the pramlintide label say about pentoxifylline?
Pramlintide label, drug interactionsThe following are examples of medications that may increase the susceptibility to hypoglycemia when administered with SYMLIN: anti-diabetic products, angiotensin converting enzyme (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, salicylates, somatostatin analogs, and sulfonamide antibiotics.
Source: FDA drug label (SymlinPen), AstraZeneca Pharmaceuticals LP, effective December 18, 2019 (SPL set 4aea30ff-eb0d-45c1-b114-3127966328ff), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pentoxifylline | Pramlintide | |
|---|---|---|
| Labeled for | n/a | Type 2 diabetes, Type 1 diabetes |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.227 per tablet 400 mg tablet | n/a |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once