What the FDA labels say about taking them together
Pentamidine diisethionate and pentamidine isethionate
Pentamidine diisethionate's FDA label of May 7, 2026 names pentamidine isethionate in its contraindications section; the pentamidine isethionate labels PlainMeds reads (2) do not name pentamidine diisethionate. The pentamidine diisethionate label: “CONTRAINDICATIONS Contraindicated in patients with a history of hypersensitivity to pentamidine isethionate.”
Check it at the source: the pentamidine diisethionate FDA label on DailyMed (effective May 7, 2026, PAI Holdings, LLC dba PAI Pharma); the pentamidine isethionate FDA label on DailyMed (effective September 13, 2022, Fresenius Kabi USA, LLC).
What does the pentamidine diisethionate label say about pentamidine isethionate?
Pentamidine diisethionate label, contraindicationsCONTRAINDICATIONS Contraindicated in patients with a history of hypersensitivity to pentamidine isethionate.
Pentamidine diisethionate label, warningsWARNINGS Fatalities due to severe hypotension, hypoglycemia, acute pancreatitis and cardiac arrhythmias have been reported in patients treated with pentamidine isethionate, both by the IM and IV routes.
Source: FDA drug label (Pentamidine Isethionate), PAI Holdings, LLC dba PAI Pharma, effective May 7, 2026 (SPL set d46aea4f-8f3f-4ce0-93d6-94e147f5a31a), via openFDA; the full label on DailyMed
What does the pentamidine isethionate label say about pentamidine diisethionate?
Pentamidine isethionate's label (effective September 13, 2022) and its 1 other brand-application label do not name pentamidine diisethionate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pentam 300), Fresenius Kabi USA, LLC, effective September 13, 2022 (SPL set cc2b635e-4840-4dc3-a177-5484371680e8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pentamidine diisethionate | Pentamidine isethionate | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once