What the FDA labels say about taking them together
Nebivolol and paroxetine
Nebivolol's FDA label of August 1, 2024 names paroxetine in its drug interactions section, and paroxetine's label names nebivolol too.
Check it at the source: the nebivolol FDA label on DailyMed (effective August 1, 2024, Allergan, Inc.); the paroxetine FDA label on DailyMed (effective February 12, 2026, Mylan Pharmaceuticals Inc.).
What does the nebivolol label say about paroxetine?
Nebivolol label, drug interactionsUse caution when BYSTOLIC is co-administered with CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine, etc.) [see Clinical Pharmacology ( 12.5 )].
Source: FDA drug label (Bystolic), Allergan, Inc., effective August 1, 2024 (SPL set 8b8ad213-1dc8-454e-a524-075685c0e1a8), via openFDA; the full label on DailyMed
What does the paroxetine label say about nebivolol?
Paroxetine label, drug interactionsExamples; propafenone, flecainide, atomoxetine, desipramine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine, venlafaxine, risperidone.
Source: FDA drug label (Paroxetine), Mylan Pharmaceuticals Inc., effective February 12, 2026 (SPL set 89dd7e24-85fc-4152-89ea-47ec2b48a1ed), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nebivolol | Paroxetine | |
|---|---|---|
| Labeled for | High blood pressure | Depression, Anxiety, Menopause symptoms |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.141 per tablet 10 mg tablet | $0.0611 per tablet 20 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once