What the FDA labels say about taking them together
Paromomycin and streptomycin
Streptomycin's FDA label of January 21, 2026 names paromomycin in its boxed warning section; the paromomycin label PlainMeds reads does not name streptomycin.
Check it at the source: the paromomycin FDA label on DailyMed (effective November 13, 2025, Waylis Therapeutics LLC); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).
What does the paromomycin label say about streptomycin?
Paromomycin's label (effective November 13, 2025) does not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Humatin), ANDA065173 (Heritage), as published by Waylis Therapeutics LLC, effective November 13, 2025 (SPL set a725f022-ec3c-430d-8021-96c861b9893c), via openFDA; the full label on DailyMed
What does the streptomycin label say about paromomycin?
Streptomycin label, boxed warningTHE CONCURRENT OR SEQUENTIAL USE OF OTHER NEUROTOXIC AND/OR NEPHROTOXIC DRUGS WITH STREPTOMYCIN SULFATE, INCLUDING NEOMYCIN, KANAMYCIN, GENTAMICIN, CEPHALORIDINE, PAROMOMYCIN, VIOMYCIN, POLYMYXIN B, COLISTIN, TOBRAMYCIN AND CYCLOSPORINE SHOULD BE AVOIDED.
Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Paromomycin | Streptomycin | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once