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What the FDA labels say about taking them together

Palopegteriparatide and teriparatide

Palopegteriparatide's FDA label of August 12, 2026 names teriparatide in its warnings and precautions section; the teriparatide labels PlainMeds reads (2) do not name palopegteriparatide. The palopegteriparatide label: “An increased incidence of osteosarcoma (a malignant bone tumor) has been reported in male and female rats treated with PTH analogs, including teriparatide.”

Check it at the source: the palopegteriparatide FDA label on DailyMed (effective August 12, 2026, Ascendis Pharma, Endocrinology, Inc.); the teriparatide FDA label on DailyMed (effective August 3, 2026, Eli Lilly and Company).

What does the palopegteriparatide label say about teriparatide?

Palopegteriparatide label, warnings and precautions

An increased incidence of osteosarcoma (a malignant bone tumor) has been reported in male and female rats treated with PTH analogs, including teriparatide.

Source: FDA drug label (Yorvipath), Ascendis Pharma, Endocrinology, Inc., effective August 12, 2026 (SPL set a1fa23fd-c434-443e-9a17-5750578c8602), via openFDA; the full label on DailyMed

What does the teriparatide label say about palopegteriparatide?

Teriparatide's label (effective August 3, 2026) and its 1 other brand-application label do not name palopegteriparatide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Forteo), Eli Lilly and Company, effective August 3, 2026 (SPL set aae667c5-381f-4f92-93df-2ed6158d07b0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Palopegteriparatide generic labelers
4Teriparatide generic labelers
PalopegteriparatideTeriparatide
Labeled forn/aOsteoporosis
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$479.95 per mL 560 mcg/2.24 mL pen
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?